Change in Taste Preference to Capsaicin and Catechin Due to Aging in Mice

Taste is a chemical sensation that primarily detects nutrients present in food, and maintenance of taste sensations important for ensuring older people have balanced nutritional diet. While several reports suggested sensitivity changes with age, the molecular mechanisms underlying this phenomenon are still unclear. Previous studies on matter focused mainly relationship between aging detection specific basic taste-inducing substances, other than these understanding how affects limited. Therefore, to understand effect has some familiar substances found our daily meals, namely capsaicin catechin, we investigated age-related preferences catechin young old C57BL/6J mice using 48-h two-bottle preference test. For stimuli, showed avoidance behavior concentration-dependent manner. However, observed there was no significant difference ratio mice. although both age groups manner, significantly higher values those This suggests declined due aging. Thus, decreases but does not.